Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.56 |
| ▸ | RXRA | P19793 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MPC2 | O95563 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68421 | 0.89 | PPARG (0.56) | PPARGRXRACYP3A4FFAR1RARG | |
| SCHEMBL1848812 | 0.84 | PPARG (0.60) | PPARGRXRACYP3A4FFAR1RARG | |
| SCHEMBL6402925 | 0.83 | PPARG (0.66) | PPARGRXRACYP3A4MPC2CYP2C8 | |
| SCHEMBL1162551 | 0.83 | PPARG (0.66) | PPARGRXRACYP3A4MPC2CYP2C8 | |
| SCHEMBL1220651 | 0.83 | PPARG (0.66) | PPARGRXRACYP3A4MPC2CYP2C8 | |
| Hydrochloric Acid SCHEMBL1162764 | 0.82 | PPARG (0.66) | PPARGRXRACYP3A4MPC2CYP2C8 | |
| SCHEMBL3117517 | 0.81 | PPARG (0.62) | PPARGRXRACYP3A4FFAR1RARG | |
| SCHEMBL15184857 | 0.80 | PPARG (0.58) | PPARGRXRACYP3A4MPC2CYP2C8 | |
| SCHEMBL3900454 | 0.78 | FFAR1 (0.62) | PPARGRXRACYP3A4MPC2CYP2C8 | |
| SCHEMBL20138268 | 0.78 | PPARG (0.66) | PPARGRXRACYP3A4MPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040024027-A1 | 5(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione hydriodide as pharmaceutical | SMITHKLINE BEECHAM PLC (GB) | 2004-02-05 | — | — | US | disclosed |