Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456204 | 0.85 | AOC3 (0.43) | ALDH1A1AOC3CES1KCNN4ACP3 | |
| SCHEMBL19164543 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRAOC3HSD17B2PTGS2 | |
| SCHEMBL5200151 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TSHRTRPA1CES1KCNN4 | |
| SCHEMBL24390577 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B2PTGS2ALOX15 | |
| SCHEMBL10800116 | 0.72 | CES1 (0.42) | ALDH1A1CES1KCNN4ALOX15 | |
| SCHEMBL19137407 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRTRPA1AOC3HSD17B2 | |
| SCHEMBL847046 | 0.70 | ALDH1A1 (0.37) | ALDH1A1TSHRAOC3RIPK1 | |
| SCHEMBL6930921 | 0.70 | ALDH1A1 (0.37) | ALDH1A1TSHRHSD17B2RIPK1TAS1R3 | |
| SCHEMBL10512565 | 0.69 | CES1 (0.40) | ALDH1A1CES1KCNN4ALOX15 | |
| SCHEMBL7691954 | 0.69 | CES1 (0.44) | ALDH1A1CES1KCNN4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216142-A4 | THERMOFORMABLE OPHTHALMIC LENS | NOVARTIS AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| EP-1216142-A1 | THERMOFORMABLE OPHTHALMIC LENS | Wesley Jessen Corporation (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001005578-A1 | THERMOFORMABLE OPHTHALMIC LENS | WESLEY-JESSEN CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |