Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925563 | 0.86 | SLC2A1 (0.53) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL30601627 | 0.83 | SLC2A1 (0.65) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5623473 | 0.83 | SLC2A1 (0.65) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5325772 | 0.82 | SLC2A1 (0.68) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL14399139 | 0.82 | SLC2A1 (0.68) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5324773 | 0.82 | SLC2A1 (0.68) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5891717 | 0.82 | SLC2A1 (0.63) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL6931984 | 0.82 | SLC2A1 (0.65) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5891367 | 0.81 | SLC2A1 (0.61) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5891404 | 0.81 | SLC2A1 (0.62) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363877-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002070470-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | claimed |