Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.76 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.76 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13464286 | 0.92 | CA2 (0.60) | CA2CAMK2ACYP26A1AKR1B1LMNA | |
| SCHEMBL75700 | 0.87 | CA2 (1.00) | CA2CAMK2AFNTAFNTBAKR1B1 | |
| Hydrogen Peroxide SCHEMBL27765042 | 0.87 | CA2 (1.00) | CA2CAMK2AFNTAFNTBAKR1B1 | |
| SCHEMBL21114405 | 0.87 | CA2 (1.00) | CA2CAMK2AFNTAFNTBAKR1B1 | |
| SCHEMBL11301868 | 0.86 | AKR1B1 (0.64) | CA2CAMK2ACYP26A1AKR1B1LMNA | |
| Water SCHEMBL27786848 | 0.85 | CA2 (0.95) | CA2CAMK2AFNTAFNTBAKR1B1 | |
| SCHEMBL7648201 | 0.85 | CA2 (0.95) | CA2CAMK2AFNTAFNTBAKR1B1 | |
| Benzene SCHEMBL28272878 | 0.85 | CA2 (0.95) | CA2CAMK2AFNTAFNTBAKR1B1 | |
| SCHEMBL3811950 | 0.85 | CA2 (0.95) | CA2CAMK2AFNTAFNTBAKR1B1 | |
| Methane SCHEMBL6154008 | 0.85 | CA2 (0.95) | CA2CAMK2AFNTAFNTBAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086079-B1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA A S (CZ) | 2003-05-07 | — | — | EP | disclosed |
| US-6303612-B1 | USED AS ANTIINFLAMMATORY AND/OR ANTIASTHMATIC AGENTS | LECIVA, A.S. (CZ) | 2001-10-16 | — | — | US | disclosed |
| EP-1086079-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | Leciva, A.S. (CZ) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999067208-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA, A.S. (CZ) | 1999-12-29 | — | — | WO | disclosed |