Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 7/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.46 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420808 | 0.82 | EGFR (0.68) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL26041464 | 0.82 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7315907 | 0.81 | EGFR (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1382333 | 0.79 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL25392727 | 0.77 | CA1 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL29238320 | 0.76 | SMN1; SMN2 (0.67) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4773166 | 0.76 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3805836 | 0.73 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL26041433 | 0.71 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1379772 | 0.71 | CA1 (0.58) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056710-B1 | DITERPENE DERIVATIVES AND ANTI-INFLAMMATORY ANALGESIC AGENTS COMPRISING THE SAME | SAE HAN PHARM CO LTD (KR) | 2003-12-10 | — | — | EP | claimed |
| US-6593363-B1 | The present invention relates to diterpene derivatives prepared from the components which are extracted from Acanthopanax Koreanum and represented by Chemical Formula (1). | SAE HAN PHARM. CO., LTD. (KR) | 2003-07-15 | — | — | US | claimed |
| EP-1056710-B1 | DITERPENE DERIVATIVES AND ANTI-INFLAMMATORY ANALGESIC AGENTS COMPRISING THE SAME | SAE HAN PHARM CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |
| US-6593363-B1 | The present invention relates to diterpene derivatives prepared from the components which are extracted from Acanthopanax Koreanum and represented by Chemical Formula (1). | SAE HAN PHARM. CO., LTD. (KR) | 2003-07-15 | — | — | US | disclosed |