Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.59 |
| ▸ | CA2 | P00918 | 7/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.58 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfacarbamide SCHEMBL154846 | 0.82 | TSHR (0.69) | CA1CA2MMP2MMP1MMP9 | |
| SCHEMBL25392727 | 0.82 | CA1 (0.61) | CA1CA2MMP2MMP1MMP9 | |
| SCHEMBL12187037 | 0.80 | CA1 (0.66) | CA1CA2MMP2MMP1MMP9 | |
| SCHEMBL7264925 | 0.80 | FLT1 (0.65) | CA1CA2MMP2MMP1MMP9 | |
| SCHEMBL29238320 | 0.80 | SMN1; SMN2 (0.67) | CA1CA2MMP2MMP1MMP9 | |
| SCHEMBL170426 | 0.80 | CA1 (0.59) | CA1CA2MMP2MMP1MMP9 | |
| SCHEMBL1382333 | 0.80 | CA1 (0.59) | CA1CA2MMP2MMP1MMP9 | |
| SCHEMBL4638239 | 0.80 | CA2 (0.59) | CA1CA2MMP2F2PRSS1 | |
| SCHEMBL370189 | 0.79 | CA2 (0.56) | CA1CA2MMP2MMP1MMP9 | |
| SCHEMBL5605338 | 0.78 | CA2 (0.54) | CA1CA2MMP2MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541748-A | Methods for treating hepatitis C | PTC THERAPEUTICS INC (US) | 2009-09-23 | — | — | CN | disclosed |
| EP-1979315-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007084435-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |