Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932709 | 1.00 | FFAR1 (0.30) | FFAR1PPARGPPARD | |
| SCHEMBL7813287 | 0.91 | — | — | |
| SCHEMBL6938180 | 0.90 | PPARG (0.32) | FFAR1PPARGPPARD | |
| SCHEMBL6938280 | 0.90 | PPARG (0.32) | FFAR1PPARGPPARD | |
| SCHEMBL6935689 | 0.80 | — | — | |
| SCHEMBL7085013 | 0.80 | ESR1 (0.33) | — | |
| SCHEMBL7085015 | 0.80 | ESR1 (0.33) | — | |
| SCHEMBL5855328 | 0.78 | — | — | |
| SCHEMBL6938216 | 0.78 | CYP3A4 (0.30) | — | |
| SCHEMBL7812643 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240156-A4 | 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2003-04-16 | — | — | EP | disclosed |
| EP-1240156-A1 | 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001042237-A1 | 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-06-14 | — | — | WO | disclosed |