Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938180 | 0.99 | PPARG (0.32) | PPARGPPARDFFAR1EDNRBEDNRA | |
| SCHEMBL6932709 | 0.90 | FFAR1 (0.30) | PPARGPPARDFFAR1 | |
| SCHEMBL6932706 | 0.90 | FFAR1 (0.30) | PPARGPPARDFFAR1 | |
| SCHEMBL6938510 | 0.86 | ESR1 (0.34) | PPARGESR1 | |
| SCHEMBL7813636 | 0.85 | DRD2 (0.33) | PPARGESR1 | |
| SCHEMBL7805794 | 0.85 | DRD2 (0.33) | PPARGESR1 | |
| SCHEMBL7812643 | 0.84 | — | — | |
| SCHEMBL7813131 | 0.82 | DRD2 (0.33) | PPARGESR1 | |
| SCHEMBL7813287 | 0.81 | — | — | |
| SCHEMBL5855973 | 0.79 | ESR1 (0.35) | PPARGPPARDFFAR1EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240155-A4 | METAL SALTS OF 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2003-04-16 | — | — | EP | disclosed |
| EP-1240155-A1 | METAL SALTS OF 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001042236-A1 | METAL SALTS OF 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-06-14 | — | — | WO | disclosed |