Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557225 | 1.00 | NOD1 (0.46) | NOD1ALOX15TGFBR1EPHX1CA2 | |
| SCHEMBL693299 | 1.00 | NOD1 (0.46) | NOD1ALOX15TGFBR1EPHX1CA2 | |
| SCHEMBL2282993 | 0.94 | NOD1 (0.48) | NOD1TGFBR1EPHX1PLA2G2APLA2G5 | |
| SCHEMBL2282988 | 0.94 | NOD1 (0.48) | NOD1TGFBR1EPHX1PLA2G2APLA2G5 | |
| SCHEMBL25253112 | 0.92 | NOD1 (0.50) | NOD1EPHX1PLA2G2APLA2G5KDM4E | |
| SCHEMBL5585038 | 0.92 | NOD1 (0.50) | NOD1EPHX1PLA2G2APLA2G5KDM4E | |
| SCHEMBL5585036 | 0.92 | NOD1 (0.50) | NOD1EPHX1PLA2G2APLA2G5KDM4E | |
| SCHEMBL24660133 | 0.92 | NOD1 (0.50) | NOD1EPHX1PLA2G2APLA2G5KDM4E | |
| SCHEMBL11799326 | 0.92 | NOD1 (0.50) | NOD1EPHX1PLA2G2APLA2G5KDM4E | |
| SCHEMBL30843340 | 0.92 | NOD1 (0.50) | NOD1EPHX1PLA2G2APLA2G5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514671-A | SERINE ALKYL, CYCLOHEXYL OR AROMATIC ETHERS IN VEHICLE; SUPPRESSING BODY ODOR BY APPLYING TO SKIN | THE GILLETTE COMPANY | 1996-05-07 | — | — | US | claimed |
| EP-0644887-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID. | SMITHKLINE BEECHAM PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| WO-1993025557-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1993-12-23 | — | — | WO | claimed |
| EP-0521871-A4 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | — | 1993-03-10 | — | — | EP | claimed |
| EP-0521871-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1993-01-13 | — | — | EP | claimed |
| WO-1991011988-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1991-08-22 | — | — | WO | claimed |
| CN-116082190-A | Industrial production method of efficient Fmoc-Ser (tBu) -OH | 常州吉恩药业有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114634460-A | Process for preparing carboxyanhydrides | 北京大学 | 2022-06-17 | — | — | CN | disclosed |
| US-10000555-B2 | Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus | SEATTLE GENETICS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| CN-104163848-A | Synthetic method of dipeptide Fmoc-Ser(tBu)-Cys-OH | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2014-11-26 | — | — | CN | disclosed |
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2013-05-16 | — | — | US | disclosed |
| EP-2585437-A2 | THIOACETATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Ardea Biosciences, Inc. (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2421844-A1 | THIOPHENE INHIBITORS OF IKK-B SERINE-THREONINE PROTEIN KINASE | Chroma Therapeutics Ltd. (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-0672670-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1995-09-20 | — | — | EP | disclosed |
| EP-0644887-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID. | SMITHKLINE BEECHAM PLC (GB) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025557-A1 | PROCESS FOR THE PREPARATION OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1993-12-23 | — | — | WO | disclosed |
| EP-0521871-A4 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0521871-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991011988-A1 | ALTERNATIVE ENZYME SUBSTRATES AS DEODORANTS | THE GILLETTE COMPANY (US) | 1991-08-22 | — | — | WO | disclosed |
| US-4457866-A | MEDICAL DIAGNOSIS | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | MMAB, PTMS, DNPEP | NOD1 3600/4885ALOX15 4357/4885TGFBR1 2721/4885 |
| US-10000555-B2 | Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus | PTMS, MMAB, DNPEP | NOD1 3581/4885ALOX15 4322/4885TGFBR1 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.