Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL6933145

C=CC(=O)OCc1cc(CCCCCCCC)ccc1C(=O)O.CCOCC.OCCOCCOCCOCCO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.45
PPARG P37231 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SLCO1B3 Q9NPD5 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43
THRB P10828 7/20 0.42
KAT8 Q9H7Z6 2/20 0.42
RARB P10826 3/20 0.42
RARA P10276 1/20 0.42
RARG P13631 1/20 0.42
THRA P10827 6/20 0.38
PTPN1 P18031 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6933146 0.88 PPARA (0.50) PPARAPPARGMEN1KMT2AALDH1A1
SCHEMBL6931823 0.85 PPARA (0.55) PPARAPPARGMEN1KMT2AUSP2
Tetraethylene Glycol SCHEMBL6931820 0.85 PPARA (0.55) PPARAPPARGMEN1KMT2AUSP2
Ether SCHEMBL6930294 0.81 THRB (0.46) PPARAMEN1KMT2AALDH1A1LMNA
SCHEMBL6930296 0.76 THRB (0.49) PPARAMEN1KMT2AALDH1A1THRB
Tetraethylene Glycol SCHEMBL15418021 0.75 TSHR (0.60) MEN1KMT2AALDH1A1CYP3A4THRB
Diethylene Glycol Monoethyl Ether SCHEMBL28142503 0.73 TSHR (0.60) MEN1KMT2AALDH1A1CYP3A4THRB
Tetraethylene Glycol SCHEMBL183154 0.73 TSHR (0.50) MEN1KMT2AALDH1A1LMNACYP3A4
SCHEMBL8418850 0.73 THRB (0.62) MEN1KMT2AUSP2ALDH1A1LMNA
Di(Hydroxyethyl)Ether SCHEMBL17821328 0.72 HCAR2 (0.47) KMT2AALDH1A1LMNACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801117-B1 Antifouling resin composition NIPPON PAINT CO LTD (JP) 2003-11-26 EP disclosed
EP-0801117-A2 Antifouling resin composition Nippon Paint Co., Ltd. (JP) 1997-10-15 EP disclosed