SCHEMBL6933250

SCHEMBL6933250

Cn1cc(CC[C@H](CO)n2cnc(C(N)=O)c2)c2cc(O)ccc21

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADA P00813 19/20 0.71
SPR P35270 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6941954 0.87 ADA (0.69) ADA
SCHEMBL6940660 0.87 ADA (0.58) ADASPR
SCHEMBL6936287 0.85 ADA (0.95) ADA
SCHEMBL6933256 0.84 ADA (0.54) ADASPR
SCHEMBL6939869 0.83 ADA (1.00) ADA
SCHEMBL6940649 0.82 ADA (1.00) ADA
SCHEMBL6941844 0.81 ADA (1.00) ADA
SCHEMBL6940669 0.80 ADA (0.52) ADASPR
SCHEMBL7848394 0.77 ADA (0.53) ADASPR
SCHEMBL7668671 0.76 ADA (0.77) ADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6596738-B1 Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-07-22 US disclosed