Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 14/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941961 | 0.87 | ADA (0.53) | ADAKDM4EHPGDHSD17B10 | |
| SCHEMBL6936293 | 0.86 | ADA (0.73) | ADA | |
| SCHEMBL6933250 | 0.84 | ADA (0.71) | ADASPR | |
| SCHEMBL6939875 | 0.84 | ADA (0.78) | ADA | |
| SCHEMBL6940669 | 0.83 | ADA (0.52) | ADASPRCYP19A1 | |
| SCHEMBL6940653 | 0.82 | ADA (0.78) | ADA | |
| SCHEMBL6941851 | 0.81 | ADA (0.79) | ADA | |
| SCHEMBL6940660 | 0.78 | ADA (0.58) | ADASPR | |
| SCHEMBL7668675 | 0.76 | ADA (0.51) | ADA | |
| SCHEMBL6941521 | 0.74 | ADA (0.60) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |