Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880114 | 1.00 | MMP2 (0.43) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL1878427 | 0.79 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL287632 | 0.79 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL498620 | 0.79 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL289725 | 0.79 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL5416450 | 0.78 | MMP2 (0.44) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL11499462 | 0.78 | MMP2 (0.44) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL7721179 | 0.78 | MMP2 (0.44) | MMP2MMP9MMP8MMP13MMP3 | |
| SCHEMBL1835994 | 0.78 | NR5A1 (0.49) | LTA4HESR1CHRM2ADRA2AADORA3 | |
| SCHEMBL9227663 | 0.78 | TDP1 (0.37) | MMP2MMP9MMP8MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852140-B1 | METHODS FOR MAKING HARDLY SOLUBLE MEDICINE AMORPHOUS | NISSAN CHEMICAL IND LTD (JP) | 2003-12-03 | — | — | EP | disclosed |
| EP-1356807-A2 | Method for converting sparingly water-soluble medical substance to amorphous state | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6462093-B1 | Method for converting sparingly water-soluble medical substance to amorphous state | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0510213-B1 | MULTILAYERED STRETCHABLE SHRINK FILM | ASAHI CHEMICAL IND (JP) | 1999-02-03 | — | — | EP | disclosed |
| EP-0852140-A1 | METHODS FOR MAKING HARDLY SOLUBLE MEDICINE AMORPHOUS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0510213-A1 | MULTILAYERED STRETCHABLE SHRINK FILM | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-10-28 | — | — | EP | disclosed |