SCHEMBL69334

SCHEMBL69334

CCOC(=O)c1ccc2c(c1)c1cc(C(=O)OCC)ccc1n2C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA7 P43166 3/20 0.56
CA9 Q16790 3/20 0.56
CA14 Q9ULX7 3/20 0.56
HCRTR1 O43613 2/20 0.54
KDM4E B2RXH2 5/20 0.52
ALDH1A1 P00352 5/20 0.52
MAPT P10636 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
RAB9A P51151 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
HPGD P15428 3/20 0.51
POLB P06746 2/20 0.51
MAPK1 P28482 2/20 0.51
HSD17B10 Q99714 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5323335 0.93 KDM4E (0.64) HCRTR1KDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL22134576 0.91 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL25811417 0.88 MAPT (0.57) CA12CA1CA2CA7CA9
SCHEMBL3209333 0.83 SCARB1 (0.44) CA12CA1CA2CA7CA9
SCHEMBL4728865 0.83 ATM (0.55) CA12CA1CA2CA7CA9
SCHEMBL23222980 0.80 TDP1 (0.57) KDM4EALDH1A1MAPTSMN1; SMN2RAB9A
SCHEMBL5797538 0.80 MAPT (0.55) CA12CA1CA2CA7CA9
SCHEMBL7929498 0.80 KDM4E (0.58) CA12CA1CA2CA7CA9
SCHEMBL15865717 0.79 PTGER4 (0.65) HCRTR1KDM4EALDH1A1MAPTSMN1; SMN2
SCHEMBL15865703 0.79 KDM4E (0.58) KDM4EALDH1A1SMN1; SMN2ESR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CA12 1221/4885CA1 550/4885CA2 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.