Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014002 | 0.87 | MEN1 (0.72) | HSD17B10HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL15706908 | 0.84 | RAB9A (0.74) | HSD17B10MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29575656 | 0.84 | HPGD (0.68) | HSD17B10HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL2502058 | 0.84 | RAB9A (0.69) | HSD17B10HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL12327192 | 0.84 | HPGD (0.68) | HSD17B10HPGDMEN1KMT2AHDAC3 | |
| Hydrochloric Acid SCHEMBL23721867 | 0.82 | RAB9A (0.67) | HSD17B10HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL4005968 | 0.82 | HPGD (0.66) | HSD17B10HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL4858118 | 0.82 | HSD17B10 (0.68) | HSD17B10HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL2189147 | 0.82 | HPGD (0.66) | HSD17B10HPGDMEN1KMT2AHDAC3 | |
| SCHEMBL15259150 | 0.82 | HPGD (0.66) | HSD17B10HPGDMEN1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114275-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2011-09-22 | — | — | WO | disclosed |