SCHEMBL693351

SCHEMBL693351

O=C(OCc1ccccc1)C1CCCN1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.63
HTR2C P28335 1/20 0.55
HTR2B P41595 1/20 0.55
BACE1 P56817 1/20 0.48
CTSC P53634 1/20 0.48
ELANE P08246 1/20 0.47
GLA P06280 1/20 0.46
FABP7 O15540 1/20 0.46
FABP5 Q01469 1/20 0.46
ALDH1A1 P00352 2/20 0.45
FKBP1A P62942 2/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL630517 1.00 TSHR (0.63) TSHRHTR2CHTR2BBACE1CTSC
SCHEMBL4069956 1.00 TSHR (0.63) TSHRHTR2CHTR2BBACE1CTSC
Hydrochloric Acid SCHEMBL1000787 0.98 TSHR (0.65) TSHRHTR2CHTR2BBACE1CTSC
Hydrochloric Acid SCHEMBL630516 0.98 TSHR (0.65) TSHRHTR2CHTR2BBACE1CTSC
Hydrochloric Acid SCHEMBL693350 0.98 TSHR (0.65) TSHRHTR2CHTR2BBACE1CTSC
SCHEMBL6727374 0.95 TSHR (0.61) TSHRHTR2CHTR2BBACE1GLA
SCHEMBL630942 0.95 TSHR (0.61) TSHRHTR2CHTR2BBACE1GLA
SCHEMBL28676037 0.94 TSHR (0.60) TSHRHTR2CHTR2BBACE1ALDH1A1
Hydrochloric Acid SCHEMBL630943 0.94 TSHR (0.64) TSHRHTR2CHTR2BBACE1ALDH1A1
Hydrochloric Acid SCHEMBL630941 0.94 TSHR (0.64) TSHRHTR2CHTR2BBACE1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106749438-A A kind of Amadori compound synthesis method 华宝香精股份有限公司 2017-05-31 CN claimed
US-20130225819-A1 USE OF AZIDES IN SYNTHESIS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-08-29 US claimed
US-5602161-A ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) 1997-02-11 US claimed
EP-0676396-A1 Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component Wakamoto Pharmaceutical Co., Ltd. (JP) 1995-10-11 EP claimed
JP-8253497-A None JP disclosed
JP-56097266-A None JP disclosed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
CN-118556062-A Compounds, pharmaceutical compositions and methods for treating, preventing or managing hyperproliferative disorders 文赛克斯制药有限责任公司 2024-08-27 CN disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
EP-3922634-B1 SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF GILEAD SCIENCES INC (US) 2023-10-25 EP disclosed
WO-2023178299-A1 PRODRUGS OF GANAXOLONE MARINUS PHARMACEUTICALS, INC. (US) 2023-09-21 WO disclosed
CN-116437913-A Pharmaceutical compounds for treating complement-mediated disorders 艾其林医药公司 2023-07-14 CN disclosed
US-4472380-A CARBOXYALKYL DIPEPTIDE DERIVATIVES MERCK & CO., INC. (US) 1984-09-18 US disclosed
WO-1984003507-A1 ENZYME INHIBITION FERRING AB (SE) 1984-09-13 WO disclosed
EP-0118280-A1 Enzyme inhibition Aktiebolaget Hässle (SE) 1984-09-12 EP disclosed
EP-0086660-A2 Renally active tetrapeptides SMITHKLINE BECKMAN CORPORATION (US) 1983-08-24 EP disclosed
US-4386075-A IMPROVING KIDNEY FUNCTION SMITHKLINE BECKMAN CORPORATION (US) 1983-05-31 US disclosed
US-4374829-A Aminoacid derivatives as antihypertensives MERCK & CO., INC. (US) 1983-02-22 US disclosed
JP-S5697266-A PROLINE DERIVATIVE AND ITS PREPARATION TANABE SEIYAKU CO LTD 1981-08-05 JP disclosed
EP-0012401-A1 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them MERCK & CO. INC. (US) 1980-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225819-A1 USE OF AZIDES IN SYNTHESIS ABL1, ABL2, TST TSHR 2217/4885HTR2C 1330/4885HTR2B 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.