Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846880 | 1.00 | — | — | |
| SCHEMBL11184724 | 0.93 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL12789681 | 0.91 | MEN1 (0.59) | ALDH1A1MEN1KMT2APOLBHSD17B10 | |
| SCHEMBL11844535 | 0.90 | — | — | |
| SCHEMBL11837046 | 0.90 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL226270 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11061943 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1499020 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6330365 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL3712422 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4392882-A | N-N-Bis(haloacyl)-diaza-cycloalkanes for protecting plants from herbicide damage | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | claimed |
| US-20030199560-A1 | Bisaryl compound and medicament for cancer treatment comprising the same | KYOWA HAKKO KOGYO CO., LTD. | 2003-10-23 | — | — | US | disclosed |
| US-6608061-B2 | Antiproliferative agents | KYOMA HAKKO KOGYO CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030018070-A1 | BISARYL COMPOUND AND MEDICAMENT FOR CANCER TREATMENT COMPRISING THE SAME | FUJIFILM CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-0990439-A1 | BISARYL COMPOUNDS AND CANCER REMEDIES CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| US-4392882-A | N-N-Bis(haloacyl)-diaza-cycloalkanes for protecting plants from herbicide damage | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| EP-0023305-B1 | USE OF N,N'-BIS(HALOGEN-ACYL)-DIAZA-CYCLOALKANES FOR THE PROTECTION OF CULTIVATED PLANTS AGAINST DAMAGE BY HERBICIDES | BAYER AG (DE) | 1983-03-02 | — | — | EP | disclosed |
| EP-0023305-A1 | Use of N,N'-bis(halogen-acyl)-diaza-cycloalkanes for the protection of cultivated plants against damage by herbicides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018070-A1 | BISARYL COMPOUND AND MEDICAMENT FOR CANCER TREATMENT COMPRISING THE SAME | AR, NR5A1, SRD5A1 | ALDH1A1 597/4885MEN1 1157/4885KMT2A 1009/4885 |
| US-20030199560-A1 | Bisaryl compound and medicament for cancer treatment comprising the same | AR, NR5A1, SRD5A1 | ALDH1A1 597/4885MEN1 1157/4885KMT2A 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.