SCHEMBL6933707

SCHEMBL6933707

CCOCCCCC[C@@H](OC(=O)c1ccc(O)cc1F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA7 P43166 4/20 0.35
CA9 Q16790 4/20 0.35
CA14 Q9ULX7 4/20 0.35
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33
ESRRG P62508 1/20 0.32
POLB P06746 1/20 0.32
SERPINE1 P05121 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8081657 1.00 CA12 (0.35) CA12CA1CA2CA7CA9
SCHEMBL8107463 0.96 CA12 (0.36) CA12CA1CA2CA7CA9
SCHEMBL8107467 0.96 CA12 (0.36) CA12CA1CA2CA7CA9
SCHEMBL8083855 0.89 CA12 (0.33) CA12CA1CA2CA7CA9
SCHEMBL8083853 0.89 CA12 (0.33) CA12CA1CA2CA7CA9
SCHEMBL8821926 0.89 CA12 (0.36) CA12CA1CA2CA7CA9
SCHEMBL9745293 0.89 ALDH1A1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL9125115 0.89 ALDH1A1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL8658793 0.86 ESR1 (0.32)
SCHEMBL8658790 0.86 ESR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962445-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS INC (JP) 2003-02-26 EP disclosed
US-6217793-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS, INC. (JP) 2001-04-17 US disclosed
EP-0780456-B1 Anti-ferroelectric liquid crystal compound and anti-ferroelectric liquid crystal composition MITSUBISHI GAS CHEMICAL CO (JP) 2000-10-11 EP disclosed
EP-0962445-A1 Acetylene compound, liquid crystal composition and liquid crystal element Mitsui Chemicals, Inc. (JP) 1999-12-08 EP disclosed
US-5723069-A Anti-ferroelectric liquid crystal compound and anti-ferroelectric liquid crystal composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-03-03 US disclosed
EP-0780456-A1 Anti-ferroelectric liquid crystal compound and anti-ferroelectric liquid crystal composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-06-25 EP disclosed