Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526054 | 1.00 | APEX1 (0.33) | APEX1GRIK1GRIK2 | |
| Trimethylammonium SCHEMBL5017422 | 0.94 | APEX1 (0.30) | APEX1 | |
| Trimethylammonium SCHEMBL5017420 | 0.94 | APEX1 (0.30) | APEX1 | |
| Trimethylammonium SCHEMBL5017423 | 0.94 | APEX1 (0.30) | APEX1 | |
| Sulfuric Acid SCHEMBL28656037 | 0.87 | GRIK1 (0.35) | APEX1GRIK1GRIK2 | |
| Sulfuric Acid Dimethyl Ester SCHEMBL10610910 | 0.83 | APEX1 (0.30) | APEX1 | |
| SCHEMBL17817 | 0.82 | — | — | |
| SCHEMBL5716965 | 0.82 | — | — | |
| SCHEMBL17819 | 0.82 | — | — | |
| SCHEMBL15846351 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995610-B1 | Ink jet recording element with overcoat layer | EASTMAN KODAK CO (US) | 2003-12-03 | — | — | EP | claimed |
| CN-1950429-B | Biodegradable grafted copolymers | FIRMENICH & CIE | 2011-08-10 | — | — | CN | disclosed |
| WO-2002018281-A1 | METHOD FOR DEWATERING OF SLUDGE | ONDEO NALCO COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |