Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL5017422 | 1.00 | APEX1 (0.30) | APEX1 | |
| Trimethylammonium SCHEMBL5017423 | 1.00 | APEX1 (0.30) | APEX1 | |
| SCHEMBL6933708 | 0.94 | APEX1 (0.33) | APEX1 | |
| SCHEMBL7526054 | 0.94 | APEX1 (0.33) | APEX1 | |
| Trimethylammonium SCHEMBL1469277 | 0.84 | GRIK1 (0.36) | — | |
| Trimethylammonium SCHEMBL679439 | 0.84 | GRIK1 (0.36) | — | |
| Trimethylammonium SCHEMBL5454856 | 0.84 | — | — | |
| Trimethylammonium SCHEMBL136535 | 0.82 | GRIK1 (0.35) | — | |
| Trimethylammonium SCHEMBL11169491 | 0.82 | GRIK1 (0.35) | — | |
| Sulfuric Acid SCHEMBL28656037 | 0.82 | GRIK1 (0.35) | APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7422680-B2 | Animal waste effluent treatment system | SHEETS SR RICHARD G | 2008-09-09 | — | — | US | disclosed |
| EP-1567456-A2 | ANIMAL WASTE EFFLUENT TREATMENT | Sheets, Richard G. (US) | 2005-08-31 | — | — | EP | disclosed |
| US-20050145552-A1 | Animal waste effluent treatment | SHEETS RICHARD G (US) | 2005-07-07 | — | — | US | disclosed |
| US-6863826-B2 | Animal waste effluent treatment | GLOBAL RESTORATIONS, INC. | 2005-03-08 | — | — | US | disclosed |
| US-20040154988-A1 | Animal waste effluent treatment | GLOBAL RESTORATIONS, INC. | 2004-08-12 | — | — | US | disclosed |
| WO-2004049787-A2 | ANIMAL WASTE EFFLUENT TREATMENT | SHEETS SR RICHARD G (US) | 2004-06-17 | — | — | WO | disclosed |
| EP-1183213-A4 | HIGHER ACTIVES DISPERSION POLYMER TO AID CLARIFICATION, DEWATERING, AND RETENTION AND DRAINAGE | NALCO CHEMICAL CO (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6413433-B1 | POLYELECTROLYTE ENHANCED SOLIDS/LIQUID SEPARATION PROCESS; CATIONIC ACRYLAMIDE DISPERSION COPOLYMER AND MICROPARTICULATE ADDED ON OPPOSITE SIDES OF BAFFLE IN EFFLUENT PIPE; INCREASED CAKE DRYNESS AND CLARITY OF FILTRATE; PAPERMILLS, TISSUE MILLS | NALCO CHEMICAL COMPANY | 2002-07-02 | — | — | US | disclosed |
| EP-1183213-A1 | HIGHER ACTIVES DISPERSION POLYMER TO AID CLARIFICATION, DEWATERING, AND RETENTION AND DRAINAGE | NALCO CHEMICAL COMPANY (US) | 2002-03-06 | — | — | EP | disclosed |
| US-6171505-B1 | OF WASTE WATER, BY ADDING A WATER SOLUBLE CATIONIC POLYMER OF DIALKYLAMINOALKYL (METH)ACRYLATE BENZYL CHLORIDE SALT, DIALKYLAMINOALKYL (METH)ACRYLATE (ALKYL)CHLORIDE SALT AND (METH)ACRYLAMIDE, MADE IN THE PRESENCE OF STABILIZER POLYMERS | NALCO CHEMICAL COMPANY | 2001-01-09 | — | — | US | disclosed |
| WO-2000061501-A1 | HIGHER ACTIVES DISPERSION POLYMER TO AID CLARIFICATION, DEWATERING, AND RETENTION AND DRAINAGE | NALCO CHEMICAL COMPANY (US) | 2000-10-19 | — | — | WO | disclosed |