Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.82 |
| ▸ | PPARG | P37231 | 9/20 | 0.82 |
| ▸ | PPARA | Q07869 | 9/20 | 0.82 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932940 | 1.00 | PPARD (0.82) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6933003 | 0.92 | PPARD (0.80) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6933007 | 0.92 | PPARD (0.80) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6862000 | 0.90 | PPARG (1.00) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6861995 | 0.90 | PPARG (1.00) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6937075 | 0.90 | PPARD (0.81) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6937919 | 0.87 | PPARD (0.69) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6939647 | 0.86 | PPARG (0.62) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6937010 | 0.86 | PPARG (0.68) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6939084 | 0.85 | PPARG (0.60) | PPARDPPARGPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |