Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 12/20 | 0.48 |
| ▸ | GNA15 | P30679 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935508 | 0.91 | FFAR1 (0.55) | FFAR1PPARDFFAR4PPARGGNA15 | |
| SCHEMBL6935270 | 0.84 | PPARD (0.51) | PPARDPPARGPPARA | |
| SCHEMBL6936573 | 0.84 | PPARG (0.52) | FFAR1PPARDPPARGPPARAMTNR1A | |
| SCHEMBL6931620 | 0.84 | PPARD (0.52) | PPARDPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL6936737 | 0.83 | FFAR1 (0.54) | FFAR1PPARDPPARGPPARA | |
| SCHEMBL6934100 | 0.79 | FFAR1 (0.51) | FFAR1PPARDPPARGPPARAMTNR1A | |
| SCHEMBL6936258 | 0.79 | FFAR1 (0.54) | FFAR1PPARDPPARGPPARA | |
| SCHEMBL6938575 | 0.79 | PPARG (0.55) | PPARDPPARGPPARA | |
| SCHEMBL6936563 | 0.78 | PPARG (0.48) | PPARDPPARGPPARA | |
| SCHEMBL6936537 | 0.78 | FFAR1 (0.51) | FFAR1PPARDFFAR4PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |