Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.55 |
| ▸ | GNA15 | P30679 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 10/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936573 | 0.91 | PPARG (0.52) | FFAR1PPARGPPARDPPARAMTNR1B | |
| SCHEMBL6933747 | 0.91 | FFAR1 (0.58) | FFAR1FFAR4GNA15PTGER3TDP1 | |
| SCHEMBL6931620 | 0.89 | PPARD (0.52) | PPARGPPARDPPARAMTNR1BMTNR1A | |
| SCHEMBL6936737 | 0.88 | FFAR1 (0.54) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL6934100 | 0.86 | FFAR1 (0.51) | FFAR1PPARGPPARDPPARAMTNR1B | |
| SCHEMBL6935270 | 0.85 | PPARD (0.51) | PPARGPPARDPPARA | |
| SCHEMBL6936258 | 0.84 | FFAR1 (0.54) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL6938575 | 0.84 | PPARG (0.55) | PPARGPPARDPPARA | |
| SCHEMBL6936537 | 0.83 | FFAR1 (0.51) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL6936563 | 0.82 | PPARG (0.48) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |