Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 9/20 | 0.47 |
| ▸ | PPARA | Q07869 | 9/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933760 | 1.00 | LMNA (0.47) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL4493742 | 0.91 | LMNA (0.57) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL4493744 | 0.91 | LMNA (0.57) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL5610633 | 0.88 | LMNA (0.55) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL5610631 | 0.88 | LMNA (0.55) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL10182711 | 0.79 | SMN1; SMN2 (0.49) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL5610798 | 0.79 | LMNA (0.56) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL5610797 | 0.79 | LMNA (0.56) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL10183468 | 0.79 | SMN1; SMN2 (0.49) | LMNAMAPK1HTTL3MBTL1PPARG | |
| SCHEMBL8305033 | 0.70 | PPARA (0.51) | LMNAMAPK1HTTL3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| CN-1219927-A | Phenylalkylcarboxylic acid derivatives | SANKYO CO (JP) | 1999-06-16 | — | — | CN | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |