SCHEMBL6933784

SCHEMBL6933784

CCc1cccc(-c2nccs2)c1I

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
ADORA2A P29274 3/20 0.38
ADORA1 P30542 3/20 0.38
ADORA3 P0DMS8 2/20 0.38
PORCN Q9H237 1/20 0.38
ADORA2B P29275 1/20 0.38
ADRA1A P35348 3/20 0.36
ADRA1D P25100 2/20 0.36
ADRA1B P35368 1/20 0.36
ADRB2 P07550 1/20 0.36
CASP6 P55212 1/20 0.36
CYP2A6 P11509 1/20 0.36
ESR1 P03372 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624878 0.83 PDPK1 (0.48) PDPK1LOXL2ADORA2AADORA1ADORA3
SCHEMBL1476093 0.83 ADORA2A (0.46) PDPK1LOXL2ADORA2AADORA1ADORA3
SCHEMBL18415038 0.79 TUBB4A (0.40) PDPK1LOXL2ADORA2AADORA1ADORA3
SCHEMBL11398268 0.74 PDPK1 (0.46) PDPK1LOXL2ADORA2AADORA1ADORA3
SCHEMBL26259560 0.72 PDPK1 (0.54) PDPK1LOXL2ADORA2AADORA1ADRA1A
SCHEMBL5692672 0.71 PDPK1 (0.64) PDPK1LOXL2ADORA2AADORA1ADRA1A
SCHEMBL1272698 0.71 ADORA2A (0.44) PDPK1LOXL2ADORA2AADORA1PORCN
SCHEMBL10977585 0.71 PDPK1 (0.53) PDPK1LOXL2ADORA2AADORA1ADRA1A
SCHEMBL16828127 0.71 SYK (0.42) PDPK1PORCNESR1HCRTR1HCRTR2
SCHEMBL5462028 0.70 PDPK1 (0.48) PDPK1LOXL2ADORA2AADORA1PORCN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6632597-B2 Color photography FUJI PHOTO FILM CO., LTD. (JP) 2003-10-14 US disclosed
US-20020155400-A1 Methine dye and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2002-10-24 US disclosed