Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930677 | 0.85 | ELANE (0.38) | ALDH1A1HSD17B10GAA | |
| SCHEMBL6935349 | 0.81 | KMT2A (0.30) | — | |
| SCHEMBL6935471 | 0.77 | NPSR1 (0.34) | SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6933587 | 0.74 | — | — | |
| SCHEMBL6935431 | 0.73 | KDM4E (0.32) | SMN1; SMN2ALDH1A1GAANPSR1 | |
| SCHEMBL6935211 | 0.73 | NPSR1 (0.31) | GAANPSR1 | |
| SCHEMBL6931568 | 0.70 | CYP2C9 (0.32) | ALDH1A1GAA | |
| SCHEMBL6933157 | 0.69 | GAA (0.46) | SMN1; SMN2ALDH1A1HSD17B10GAA | |
| SCHEMBL6935248 | 0.68 | — | — | |
| SCHEMBL6935778 | 0.67 | MEN1 (0.48) | SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |