SCHEMBL6935211

SCHEMBL6935211

COC(=O)C1=NN(C(C)C)C(=O)C1(O)O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.31
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6933866 0.81 GAA (0.32) GAATDP1
SCHEMBL6935471 0.77 NPSR1 (0.34) NPSR1
SCHEMBL6934456 0.74 GAA (0.32) GAATDP1
SCHEMBL6933819 0.73 SMN1; SMN2 (0.34) NPSR1GAA
SCHEMBL6935431 0.73 KDM4E (0.32) NPSR1GAA
SCHEMBL6928265 0.71 GAA (0.39) GAATDP1
SCHEMBL6933157 0.69 GAA (0.46) GAA
SCHEMBL8491902 0.69 KMT2A (0.45) NPSR1GAATDP1
SCHEMBL6931334 0.67 GAA (0.32) GAATDP1
SCHEMBL6933873 0.67 GAA (0.33) GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US claimed
EP-0903342-B1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics OREAL (FR) 2003-12-17 EP disclosed
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US disclosed
EP-0903342-A1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics L'OREAL (FR) 1999-03-24 EP disclosed