Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698329 | 0.86 | NPC1 (0.51) | NPC1RAB9AHTTCTSDMAPT | |
| SCHEMBL27313373 | 0.84 | NPC1 (0.50) | NPC1RAB9AHTTCTSDMAPT | |
| SCHEMBL855233 | 0.82 | MAPT (0.57) | NPC1RAB9AHTTCTSDMAPT | |
| SCHEMBL9152770 | 0.79 | NPC1 (0.49) | NPC1RAB9AHTTCTSDMAPT | |
| SCHEMBL8396771 | 0.79 | CTSD (0.51) | NPC1RAB9AHTTCTSDMAPT | |
| SCHEMBL9559943 | 0.79 | CTSD (0.56) | NPC1RAB9AHTTCTSDMAPT | |
| SCHEMBL27586416 | 0.79 | CTSD (0.51) | NPC1RAB9AHTTCTSDMAPT | |
| SCHEMBL16613085 | 0.77 | MAPT (0.50) | NPC1RAB9AMAPTALDH1A1ABCG2 | |
| SCHEMBL3990682 | 0.77 | SMN1; SMN2 (0.53) | NPC1RAB9AHTTCTSDMAPT | |
| SCHEMBL27758670 | 0.77 | CTSD (0.53) | NPC1RAB9AHTTCTSDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363869-A2 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | Clariant (France) S.A. (FR) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002067847-A2 | PROCESS FOR THE PREPARATION OF ALKYL BENZOYLACRYLATES | CLARIANT (FRANCE) (FR) | 2002-09-06 | — | — | WO | disclosed |