Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108442 | 0.88 | TP53 (0.47) | EPHX2TP53GAASMN1; SMN2 | |
| SCHEMBL6827910 | 0.88 | TP53 (0.47) | EPHX2TP53GAASMN1; SMN2 | |
| SCHEMBL13339539 | 0.88 | TP53 (0.47) | EPHX2TP53GAASMN1; SMN2 | |
| SCHEMBL2473642 | 0.86 | EPHX2 (0.34) | EPHX2TP53ADORA3GAAGRM1 | |
| SCHEMBL15588225 | 0.86 | EPHX2 (0.34) | EPHX2TP53ADORA3GAAGRM1 | |
| SCHEMBL19774486 | 0.84 | EPHX2 (0.33) | EPHX2TP53ADORA3GAAGRM1 | |
| SCHEMBL21360459 | 0.82 | MAPT (0.51) | GAA | |
| SCHEMBL17453219 | 0.82 | TP53 (0.47) | EPHX2TP53GAASMN1; SMN2 | |
| SCHEMBL1957759 | 0.82 | MAPT (0.51) | GAA | |
| SCHEMBL28003109 | 0.82 | CHRNB2 (0.38) | EPHX2ADORA3GRM1MAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |