Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938087 | 0.90 | SLC9A1 (0.54) | SLC9A1 | |
| SCHEMBL6935396 | 0.88 | SLC9A1 (0.38) | SLC9A1 | |
| SCHEMBL6930558 | 0.87 | SLC9A1 (0.59) | SLC9A1KCNH2 | |
| SCHEMBL6935096 | 0.85 | SLC9A1 (0.57) | SLC9A1KCNH2 | |
| SCHEMBL6934404 | 0.85 | SLC9A1 (0.52) | SLC9A1 | |
| SCHEMBL6935465 | 0.83 | SLC9A1 (0.72) | SLC9A1 | |
| SCHEMBL6936927 | 0.82 | SLC9A1 (0.53) | SLC9A1KCNH2 | |
| SCHEMBL6938917 | 0.82 | SLC9A1 (0.75) | SLC9A1 | |
| SCHEMBL8538459 | 0.82 | AKR1C3 (0.33) | — | |
| SCHEMBL6932999 | 0.82 | SLC9A1 (0.58) | SLC9A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758644-B1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0758644-A1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |