Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14322616 | 0.85 | GRIA1 (0.57) | GRIA1SLC6A3 | |
| SCHEMBL16920992 | 0.82 | PDE10A (0.55) | — | |
| SCHEMBL16283463 | 0.79 | PDE10A (0.44) | — | |
| SCHEMBL2482152 | 0.76 | GRIA1 (0.67) | GRIA1 | |
| SCHEMBL14685172 | 0.76 | PDE10A (0.40) | GRIA1 | |
| SCHEMBL2482640 | 0.76 | GRIA1 (0.63) | GRIA1 | |
| SCHEMBL6937905 | 0.76 | GRIA1 (0.66) | GRIA1 | |
| SCHEMBL30366310 | 0.75 | GRIA1 (0.51) | GRIA1 | |
| SCHEMBL2482568 | 0.75 | GRIA1 (0.65) | GRIA1 | |
| SCHEMBL6934688 | 0.75 | PDE10A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110545-A1 | IMIDAZO [1, 2 -A] PYRAZINE DERIVATIVES AND THEIR USE FOR THE PREVENTION OR TREATMENT OF NEUROLOGICAL, PSYCHIATRIC AND METABOLIC DISORDERS AND DISEASES | JANSSEN PHARMACEUTICA NV (BE) | 2011-09-15 | — | — | WO | disclosed |