Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934688 | 0.86 | PDE10A (0.53) | PDE10A | |
| SCHEMBL2447847 | 0.86 | PDE10A (0.57) | PDE10A | |
| SCHEMBL6934731 | 0.82 | GRIA1 (0.57) | — | |
| SCHEMBL16283463 | 0.81 | PDE10A (0.44) | PDE10A | |
| SCHEMBL6937842 | 0.81 | PDE10A (0.49) | PDE10A | |
| SCHEMBL30366310 | 0.80 | GRIA1 (0.51) | — | |
| SCHEMBL2484005 | 0.79 | — | — | |
| SCHEMBL6937988 | 0.78 | ALDH1A1 (0.47) | — | |
| SCHEMBL14329229 | 0.78 | — | — | |
| SCHEMBL2486553 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545055-B1 | Imidazo[1,2-a]pyrazine derivatives and their use for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-09 | — | — | EP | disclosed |
| US-9550784-B2 | Inhibitors of phosphodiesterase 10 enzyme | Beerse Pharmaceutica NV (BE) | 2017-01-24 | — | — | US | disclosed |
| US-20150203498-A1 | INHIBITORS OF PHOSPHODIESTERASE 10 ENZYME | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203498-A1 | INHIBITORS OF PHOSPHODIESTERASE 10 ENZYME | PDE12, PDE5A, PDE2A | PDE10A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.