Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.75 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.58 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932533 | 0.89 | SLC9A1 (0.70) | SLC9A1 | |
| SCHEMBL6938299 | 0.89 | SLC9A1 (0.70) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL6935100 | 0.88 | SLC9A1 (0.57) | SLC9A1 | |
| SCHEMBL6934544 | 0.88 | SLC9A1 (0.75) | SLC9A1SLC9A3SLC9A2 | |
| Rimeporide SCHEMBL1019633 | 0.87 | SLC9A1 (1.00) | SLC9A1 | |
| Rimeporide SCHEMBL30309010 | 0.87 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL6932945 | 0.86 | SLC9A1 (0.73) | SLC9A1 | |
| SCHEMBL7069444 | 0.86 | SLC9A1 (0.65) | SLC9A1 | |
| Rimeporide SCHEMBL1022632 | 0.85 | SLC9A1 (0.97) | SLC9A1 | |
| Rimeporide SCHEMBL16712399 | 0.85 | SLC9A1 (0.97) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758644-B1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0758644-A1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |