⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935363 | 1.00 | — | — | |
| SCHEMBL6935361 | 1.00 | — | — | |
| SCHEMBL6938069 | 1.00 | — | — | |
| SCHEMBL6938065 | 1.00 | — | — | |
| SCHEMBL23373578 | 0.84 | CRBN (0.39) | — | |
| SCHEMBL357257 | 0.76 | — | — | |
| SCHEMBL12160740 | 0.76 | — | — | |
| SCHEMBL24378258 | 0.74 | — | — | |
| SCHEMBL1643837 | 0.74 | — | — | |
| SCHEMBL18612505 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420694-B2 | Pyrrolidin-2-one derivatives as androgen receptor modulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20110098336-A1 | PYRROLIDIN-2-ONE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-04-28 | — | — | US | disclosed |
| CN-1158257-C | Novel amino pyrroline compound, its prepn. method and pharmaceutical compositions contg. same | ɪά��ʵ���� | 2004-07-21 | — | — | CN | disclosed |
| EP-1101756-B1 | Aminopyrrolidine derivatives, processes for their preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| US-6300366-B1 | FOR THERAPY OF CARDIOVASCULAR DISEASES, ESPECIALLY ARTERIAL HYPERTENSION, ARRHYTHMIA | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| CN-1298872-A | Novel amino pyrroline compound, its prepn. method and pharmaceutical compositions contg. same | ARID ET CIE (FR) | 2001-06-13 | — | — | CN | disclosed |
| EP-1101756-A1 | Aminopyrrolidine derivatives, processes for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-05-23 | — | — | EP | disclosed |