⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935357 | 1.00 | — | — | |
| SCHEMBL6935361 | 1.00 | — | — | |
| SCHEMBL6938069 | 1.00 | — | — | |
| SCHEMBL6938065 | 1.00 | — | — | |
| SCHEMBL23373578 | 0.84 | CRBN (0.39) | — | |
| SCHEMBL357257 | 0.76 | — | — | |
| SCHEMBL12160740 | 0.76 | — | — | |
| SCHEMBL24378258 | 0.74 | — | — | |
| SCHEMBL1643837 | 0.74 | — | — | |
| SCHEMBL18612505 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107254026-A | Polymer and nano-gel material and its preparation and application | 庄臣及庄臣视力保护公司 | 2017-10-17 | — | — | CN | claimed |
| EP-2705073-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | Johnson & Johnson Vision Care Inc. (US) | 2014-03-12 | — | — | EP | claimed |
| WO-2012151134-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2012-11-08 | — | — | WO | claimed |
| WO-2021105916-A1 | SULFONAMIDE COMPOUNDS TARGETING CD73 AND ADENOSINE RECEPTORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2021-06-03 | — | — | WO | disclosed |
| US-10385034-B2 | Flavonoid IL-17A inhibitors | THE CLEVELAND CLINIC FOUNDATION (US) | 2019-08-20 | — | — | US | disclosed |
| CN-107936204-A | Polymer and nano-gel material and its preparation and application | 庄臣及庄臣视力保护公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-104334596-B | Polymer and nanogel materials and methods of making and using the same | 庄臣及庄臣视力保护公司 | 2017-12-05 | — | — | CN | disclosed |
| CN-107254026-A | Polymer and nano-gel material and its preparation and application | 庄臣及庄臣视力保护公司 | 2017-10-17 | — | — | CN | disclosed |
| WO-2017101884-A1 | INDOLAMINE 2,3-DIOXYGENASE INHIBITOR AND PREPARATION METHOD AND USE THEREOF | 江苏豪森药业集团有限公司 | 2017-06-22 | — | — | WO | disclosed |
| CN-104350076-B | Polymer and nanogel materials, and methods of making and using the same | 庄臣及庄臣视力保护公司 | 2017-05-17 | — | — | CN | disclosed |
| EP-2855547-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | Johnson & Johnson Vision Care Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| US-7973162-B2 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-05 | — | — | US | disclosed |
| CN-101959664-A | Methods and systems for processing silicone hydrogel ophthalmic lenses for improved lens transfer | JOHNSON & JOHNSON VISION CARE | 2011-01-26 | — | — | CN | disclosed |
| CN-101835846-A | Silicone hydrogels with amino surface groups | BAUSCH & LOMB | 2010-09-15 | — | — | CN | disclosed |
| US-20090099222-A1 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2009-04-16 | — | — | US | disclosed |
| CN-1158257-C | Novel amino pyrroline compound, its prepn. method and pharmaceutical compositions contg. same | ɪά��ʵ���� | 2004-07-21 | — | — | CN | disclosed |
| EP-1101756-B1 | Aminopyrrolidine derivatives, processes for their preparation and pharmaceutical compositions comprising them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| US-6300366-B1 | FOR THERAPY OF CARDIOVASCULAR DISEASES, ESPECIALLY ARTERIAL HYPERTENSION, ARRHYTHMIA | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| CN-1298872-A | Novel amino pyrroline compound, its prepn. method and pharmaceutical compositions contg. same | ARID ET CIE (FR) | 2001-06-13 | — | — | CN | disclosed |
| EP-1101756-A1 | Aminopyrrolidine derivatives, processes for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 2001-05-23 | — | — | EP | disclosed |