Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.92 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639 | 0.96 | ALDH1A1 (1.00) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| SCHEMBL473081 | 0.96 | ALDH1A1 (1.00) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Ethylene SCHEMBL7955374 | 0.92 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Ammonia Solution, Strong SCHEMBL28837807 | 0.92 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| SCHEMBL10426886 | 0.92 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Hydrochloric Acid SCHEMBL23581954 | 0.92 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Water SCHEMBL20378930 | 0.92 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| SCHEMBL29229894 | 0.92 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| SCHEMBL22496003 | 0.92 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1TP53 | |
| Water SCHEMBL28759143 | 0.92 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2063872-B1 | CONTROLLED RELEASE ORAL DOSAGE FORMULATIONS COMPRISING A CORE AND ONE OR MORE BARRIER LAYERS | JAGOTEC AG (CH) | 2015-05-06 | — | — | EP | claimed |
| EP-1019029-B1 | MONOLITHIC SYSTEM CONTAINING ONE OR MORE DRUGS, CONSISTING OF THREE LAYERS WITH DIFFERENT RELEASE MECHANISMS | CHIESI FARMA SPA (IT) | 2003-09-03 | — | — | EP | claimed |