Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935335 | 0.89 | MEN1 (0.46) | KMT2AELANESMN1; SMN2RAB9ALMNA | |
| SCHEMBL6932808 | 0.88 | MAPT (0.42) | ALDH1A1KMT2AELANESMN1; SMN2RAB9A | |
| SCHEMBL6932549 | 0.87 | GAA (0.43) | ALDH1A1KMT2ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL6933446 | 0.83 | ELANE (0.41) | ALDH1A1KMT2AELANESMN1; SMN2RAB9A | |
| SCHEMBL6928227 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1KMT2AELANESMN1; SMN2RAB9A | |
| SCHEMBL8491902 | 0.77 | KMT2A (0.45) | ALDH1A1KMT2ASMN1; SMN2RAB9ALMNA | |
| SCHEMBL6935414 | 0.77 | ELANE (0.44) | ALDH1A1KMT2AELANESMN1; SMN2RAB9A | |
| SCHEMBL6935784 | 0.77 | APP (0.49) | ALDH1A1KMT2ASMN1; SMN2RAB9AAPP | |
| SCHEMBL6934726 | 0.76 | APP (0.48) | ALDH1A1KMT2AELANESMN1; SMN2LMNA | |
| SCHEMBL6936525 | 0.75 | GAA (0.39) | ALDH1A1KMT2AELANESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |