SCHEMBL6935335

SCHEMBL6935335

COC1=NN(c2ccc(OC)cc2)C(=O)C1(O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
GAA P10253 1/20 0.46
APP P05067 1/20 0.44
ELANE P08246 1/20 0.43
MGLL Q99685 1/20 0.41
HSD11B1 P28845 4/20 0.40
POLB P06746 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 1/20 0.37
CA12 O43570 1/20 0.37
PGR P06401 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935622 0.89 ALDH1A1 (0.37) MEN1KMT2AGAAAPPELANE
SCHEMBL6935414 0.87 ELANE (0.44) MEN1KMT2AGAAAPPELANE
SCHEMBL6932808 0.86 MAPT (0.42) MEN1KMT2AGAAELANEMAPT
SCHEMBL6932549 0.86 GAA (0.43) MEN1KMT2AGAAPOLBCYP1A2
SCHEMBL6934726 0.84 APP (0.48) MEN1KMT2AGAAAPPELANE
SCHEMBL6935629 0.82 APP (0.49) MEN1KMT2AGAAAPPELANE
SCHEMBL6933158 0.81 MEN1 (0.46) MEN1KMT2AGAAAPPELANE
SCHEMBL6935627 0.81 MEN1 (0.43) MEN1KMT2AGAAAPPELANE
SCHEMBL6935778 0.80 MEN1 (0.48) MEN1KMT2AGAAAPPELANE
SCHEMBL6932816 0.79 CES2 (0.44) MEN1KMT2AGAAAPPHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US claimed
EP-0903342-B1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics OREAL (FR) 2003-12-17 EP disclosed
US-5958382-A ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR SOCIETE L'OREAL S.A. (FR) 1999-09-28 US disclosed
EP-0903342-A1 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics L'OREAL (FR) 1999-03-24 EP disclosed