Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2955263 | 0.98 | KAT2B (0.35) | KAT2BKDM4ESMN1; SMN2TSHRLMNA | |
| SCHEMBL12534295 | 0.68 | KDM4E (0.36) | KAT2BKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL4202223 | 0.68 | KAT2B (0.37) | KAT2BKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL27596901 | 0.67 | — | — | |
| Bromide SCHEMBL2954433 | 0.67 | KAT2B (0.36) | KAT2BKDM4ESMN1; SMN2TSHRLMNA | |
| SCHEMBL29546089 | 0.67 | KDM4E (0.35) | KAT2BKDM4ESMN1; SMN2TSHRLMNA | |
| Bromide SCHEMBL2761185 | 0.67 | SMN1; SMN2 (0.35) | KAT2BKDM4ESMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL30620918 | 0.67 | KDM4E (0.35) | KAT2BKDM4ESMN1; SMN2TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL27643707 | 0.65 | TSHR (0.32) | TSHR | |
| SCHEMBL4189303 | 0.64 | KAT2B (0.37) | KAT2BKDM4ESMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |