SCHEMBL6935672

SCHEMBL6935672

COCCCCCNC(=N)N

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 3/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.42
ALOX15 P16050 1/20 0.42
RECQL P46063 1/20 0.38
DDAH1 O94760 1/20 0.36
EPHX1 P07099 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
EPHX2 P34913 3/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SPHK1 Q9NYA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6936352 0.98 SMN1; SMN2 (0.47) MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1
SCHEMBL1427269 0.91
SCHEMBL10725759 0.83 MEN1 (0.53) MEN1CYP1A2KMT2ASMN1; SMN2GAA
SCHEMBL395191 0.82
SCHEMBL11724478 0.82 POLB (0.48) ALDH1A1TSHRRECQLEPHX1EPHX2
SCHEMBL1923256 0.82 SMN1; SMN2 (0.67) MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1
SCHEMBL3069140 0.82 SMN1; SMN2 (0.67) MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1
SCHEMBL10728151 0.82 SMN1; SMN2 (0.67) MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1
SCHEMBL11882788 0.82 SMN1; SMN2 (0.67) MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1
SCHEMBL3072659 0.82 SMN1; SMN2 (0.67) MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805674-B1 SKIN AND HAIR COSMETIC COMPOSITIONS KAO CORP (JP) 2003-03-12 EP disclosed
US-6348200-B1 OXYALKYLAMIDE OR AMINE DERIVATIVES;AT LEAST ONE OF POLYHYDRIC ALCOHOLS, OR VEGETABLE EXTRACTS, OR ORGANIC ACIDS; IMPROVES WATER-RETAINING ABILITY OF HORNY LAYER, CURES ROUGHNESS AND PREVENTS WRINKLES KAO CORPORATION (JP) 2002-02-19 US disclosed
US-6187955-B1 A MOISTURIZER FOR SOFTENING SKINS; USEFUL AS COMPONENTS OF COSMETIC FORMULATIONS KAO CORPORATION (JP) 2001-02-13 US disclosed
US-5723133-A GUANIDINE WITH ORGANIC ACID FOR SKIN SOFTENING KAO CORPORATION (JP) 1998-03-03 US disclosed
EP-0805674-A1 SKIN AND HAIR COSMETIC COMPOSITIONS Kao Corporation (JP) 1997-11-12 EP disclosed
WO-1997014401-A1 SKIN AND HAIR COSMETIC COMPOSITIONS KAO CORPORATION (JP) 1997-04-24 WO disclosed