⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL395610 | 0.98 | — | — | |
| Sulfuric Acid SCHEMBL11559579 | 0.89 | ALOX15 (0.49) | — | |
| SCHEMBL4094463 | 0.87 | MEN1 (0.38) | — | |
| SCHEMBL6938635 | 0.87 | MEN1 (0.38) | — | |
| SCHEMBL1427269 | 0.86 | — | — | |
| SCHEMBL6936352 | 0.84 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL1345487 | 0.83 | MEN1 (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL5775856 | 0.83 | HPGD (0.37) | — | |
| SCHEMBL4093658 | 0.82 | DDAH1 (0.40) | — | |
| SCHEMBL6935672 | 0.82 | MEN1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101744-B2 | Isolation and purification of nucleic acids with a solid phase | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-01-24 | — | — | US | claimed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | claimed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | claimed |
| US-20080319182-A1 | ISOLATION AND PURIFICATION OF NUCLEIC ACIDS WITH A SOLID PHASE | ROCHE DIAGNOSTICS GMBH (DE) | 2008-12-25 | — | — | US | claimed |
| EP-1983051-A2 | Isolation and purification of nucleic acid molecules with solid phase | Roche Diagnostics GmbH (DE) | 2008-10-22 | — | — | EP | claimed |
| CN-101289661-A | Isolation and purification of nucleic acid molecules with solid phase | HOFFMANN LA ROCHE (CH) | 2008-10-22 | — | — | CN | claimed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | claimed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | claimed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | claimed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0401010-A2 | Pyranyl cyanoguanidine derivatives | E.R. Squibb & Sons, Inc. (US) | 1990-12-05 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| US-20250340530-A1 | GCN2 INHIBITOR (as amended) | IP2IPO INNOVATIONS LTD (GB) | 2025-11-06 | — | — | US | disclosed |
| EP-4522610-A1 | GCN2 INHIBITORR | IP2IPO Innovations Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119451955-A | GCN2 inhibitors | IP2IPO创新有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-5223498-A | Hypoglycemic agents | THE BOOTS COMPANY PLC (GB) | 1993-06-29 | — | — | US | disclosed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| CN-1057648-A | Therapeutical agent | BOOTS CO PLC (GB) | 1992-01-08 | — | — | CN | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |