Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142433 | 0.78 | HRH1 (0.60) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL3334897 | 0.77 | HRH1 (0.64) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL31737574 | 0.76 | IDO1 (0.52) | ALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL809192 | 0.76 | IDO1 (0.52) | ALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL313132 | 0.75 | HRH1 (0.62) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL1196716 | 0.74 | HRH1 (0.71) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL2031145 | 0.74 | HRH1 (0.60) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL194417 | 0.74 | HRH1 (0.60) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL2046663 | 0.74 | HRH1 (0.60) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL327806 | 0.74 | SLC6A4 (0.63) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566547-B1 | 3-alkoxy-2-phenylacrylic acid derivatives | ZENECA LIMITED (GB) | 2003-05-20 | — | — | US | disclosed |
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-5315025-A | Acrylate ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-05-24 | — | — | US | disclosed |
| US-5286894-A | Phenyl acrylic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |
| EP-0431328-A2 | Fungicides | ZENECA LIMITED (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0178826-A2 | Fungicides | ZENECA LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |