SCHEMBL327806

SCHEMBL327806

CCc1ccccc1Oc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.63
SLC6A2 P23975 3/20 0.63
RIPK1 Q13546 1/20 0.63
HRH1 P35367 1/20 0.60
SLC6A3 Q01959 2/20 0.50
MAPT P10636 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HTR2A P28223 3/20 0.49
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
KMT2A Q03164 1/20 0.48
AR P10275 1/20 0.48
CYP19A1 P11511 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL28150140 0.98 SLC6A4 (0.61) SLC6A4SLC6A2RIPK1HRH1SLC6A3
SCHEMBL475213 0.86 L3MBTL1 (0.57) SLC6A4SLC6A2RIPK1SLC6A3MAPT
SCHEMBL5023464 0.86 SLC6A4 (0.67) SLC6A4SLC6A2RIPK1HRH1SLC6A3
SCHEMBL18313564 0.86 AR (0.51) SLC6A4SLC6A2RIPK1HRH1SLC6A3
SCHEMBL5024669 0.86 SLC6A4 (0.67) SLC6A4SLC6A2RIPK1HRH1SLC6A3
Tetraethylene Glycol SCHEMBL10689181 0.85 SLC6A2 (0.49) SLC6A4SLC6A2RIPK1HRH1SLC6A3
SCHEMBL29552882 0.84 HRH1 (0.53) SLC6A4SLC6A2RIPK1HRH1SLC6A3
SCHEMBL12929642 0.84 SLC6A4 (0.68) SLC6A4SLC6A2RIPK1SLC6A3MAPT
SCHEMBL22167231 0.84 SLC6A4 (0.68) SLC6A4SLC6A2RIPK1HRH1SLC6A3
SCHEMBL553699 0.84 HRH1 (0.53) SLC6A4SLC6A2RIPK1HRH1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286478-B Ni-Cu alloy is catalyzed and prepared into lignin-derived phenolic monomer through selective hydrogenation and aromatic ring protection mechanism 曲阜师范大学 2023-11-24 CN claimed
CN-115286478-A Method for preparing lignin-derived phenolic monomer by catalyzing Ni-Cu alloy through selective hydrogenation and aromatic ring protection mechanism 曲阜师范大学 2022-11-04 CN claimed
CN-115007184-A Nitrogen-doped carbon-loaded ruthenium-iron bimetallic catalyst and preparation method and application thereof 中国矿业大学 2022-09-06 CN claimed
CN-113751054-B SiO (silicon dioxide)2Coated molecular sieve supported bimetallic catalyst and preparation method and application thereof 武汉工程大学 2022-07-19 CN claimed
CN-113181921-B High-activity Ni/ACP catalyst and preparation method and application thereof 中国矿业大学 2022-03-25 CN claimed
CN-113350570-B Artificial joint with self-repairing textured composite film structure and preparation method thereof 湘潭大学 2022-03-08 CN claimed
CN-113083297-B Preparation method of high-activity and extremely-low-load ruthenium catalyst Ru @ ZIF-8 and application of catalyst Ru @ ZIF-8 in aspect of catalytic hydrogenation 中国矿业大学 2022-01-21 CN claimed
CN-110947379-B Preparation of high-activity ruthenium catalyst and application of high-activity ruthenium catalyst in room-temperature catalytic hydrogenation 中国矿业大学 2020-08-18 CN claimed
CN-111138248-A Application of recyclable palladium-based catalyst in lignin hydrogenation degradation 广东工业大学 2020-05-12 CN claimed
US-10392317-B2 Methods of producing para-xylene and terephthalic acid MICROMIDAS, INC. (US) 2019-08-27 US claimed
US-20150266793-A1 METHODS OF PRODUCING PARA-XYLENE AND TEREPHTHALIC ACID MICROMIDAS, INC. (US) 2015-09-24 US claimed
EP-2895446-A1 METHODS OF PRODUCING PARA-XYLENE AND TEREPHTHALIC ACID Micromidas, Inc. (US) 2015-07-22 EP claimed
US-8889938-B2 Methods of producing para-xylene MICROMIDAS, INC. (US) 2014-11-18 US claimed
WO-2014043468-A1 METHODS OF PRODUCING PARA-XYLENE AND TEREPHTHALIC ACID MICROMIDAS INC. (US) 2014-03-20 WO claimed
US-20130245316-A1 METHODS OF PRODUCING PARA-XYLENE AND TEREPHTHALIC ACID MICROMIDAS, INC. (US) 2013-09-19 US claimed
US-20240016775-A1 ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR FUKANG (SHANGHAI) HEALTH TECHNOLOGY CO., LTD (CN) 2024-01-18 US disclosed
US-20230382865-A1 HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2023-11-30 US disclosed
EP-0030333-A1 Alkyldiphenyl-ether sulfonic acid hydrazides, their production and use as blowing agents BAYER AG (DE) 1981-06-17 EP disclosed
US-4252624-A FREE RADICAL CATALYST, WATER ELI LILLY AND COMPANY (US) 1981-02-24 US disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382865-A1 HISTONE DEMETHYLASE 5 INHIBITORS AND USES THEREOF KDM5A, KDM5B, KDM5C SLC6A4 3312/4885SLC6A2 3157/4885RIPK1 2959/4885
US-20240016775-A1 ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR PARP3, PARP1, PARP4 SLC6A4 2710/4885SLC6A2 4625/4885RIPK1 254/4885
US-20130245316-A1 METHODS OF PRODUCING PARA-XYLENE AND TEREPHTHALIC ACID DCXR, DDT, HPD SLC6A4 2981/4885SLC6A2 4230/4885RIPK1 4242/4885
US-10392317-B2 Methods of producing para-xylene and terephthalic acid DCXR, DDT, HPD SLC6A4 2981/4885SLC6A2 4230/4885RIPK1 4242/4885
US-20150266793-A1 METHODS OF PRODUCING PARA-XYLENE AND TEREPHTHALIC ACID DCXR, DDT, HPD SLC6A4 2981/4885SLC6A2 4230/4885RIPK1 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.