Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068243 | 0.76 | KMT2A (0.41) | MTNR1AMTNR1BKMT2ASLC6A2SLC6A4 | |
| SCHEMBL10509688 | 0.71 | MTNR1A (0.50) | MTNR1AMTNR1BKMT2ACA12CA1 | |
| SCHEMBL10564065 | 0.71 | MTNR1A (0.43) | MTNR1AMTNR1BKMT2ACA12CA1 | |
| SCHEMBL5962399 | 0.70 | CA1 (0.50) | MTNR1AMTNR1BKMT2ASLC6A2SLC6A4 | |
| SCHEMBL6068422 | 0.70 | MTNR1A (0.46) | MTNR1AMTNR1BKMT2ACA12CA1 | |
| SCHEMBL6068419 | 0.70 | MTNR1A (0.46) | MTNR1AMTNR1BKMT2ACA12CA1 | |
| SCHEMBL6068534 | 0.70 | MTNR1A (0.46) | MTNR1AMTNR1BKMT2ACA12CA1 | |
| SCHEMBL29144729 | 0.70 | KMT2A (0.39) | MTNR1AMTNR1BKMT2ASLC6A2SLC6A4 | |
| SCHEMBL9621601 | 0.69 | MTNR1A (0.55) | MTNR1AMTNR1BKMT2ACA12CA1 | |
| SCHEMBL28091963 | 0.69 | CA1 (0.48) | MTNR1AMTNR1BKMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |