SCHEMBL6935812

SCHEMBL6935812

O=C(O)COC(F)(F)C(F)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
CTH P32929 1/20 0.35
CBS P35520 1/20 0.35
THPO P40225 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088592 0.84 TSHR (0.33) TSHRCTHCBSTHPOSMN1; SMN2
SCHEMBL12269559 0.82 TSHR (0.41) TSHRCTHCBSTHPOSMN1; SMN2
SCHEMBL2524434 0.77 TSHR (0.32) TSHRCTHCBSTHPOSMN1; SMN2
SCHEMBL6938567 0.77 TSHR (0.32) TSHRCTHCBSTHPOSMN1; SMN2
SCHEMBL7671798 0.75
SCHEMBL1118445 0.74
SCHEMBL14722054 0.73 MAPK1 (0.44) TSHRSMN1; SMN2
SCHEMBL15547167 0.73 TSHR (0.30) TSHRSMN1; SMN2
SCHEMBL1607406 0.72 TSHR (0.39) TSHRCTHCBSTHPOSMN1; SMN2
SCHEMBL31465221 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0600294-B1 Polyether substituted imide compounds and their use BAYER AG (DE) 2003-02-19 EP disclosed
EP-0600294-A2 Polyether substituted imide compounds and their use BAYER AG (DE) 1994-06-08 EP disclosed
EP-0571832-A2 Imides and their salts and their use as surface active agents BAYER AG (DE) 1993-12-01 EP disclosed