SCHEMBL1118445

SCHEMBL1118445

O=C(O)COC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1607406 0.97 TSHR (0.39)
SCHEMBL1607266 0.79
SCHEMBL15677656 0.78
SCHEMBL11669967 0.78 TSHR (0.38)
SCHEMBL31681398 0.78 TSHR (0.38)
SCHEMBL817363 0.78 CES2 (0.34)
SCHEMBL6415792 0.77
SCHEMBL23637744 0.74
SCHEMBL22118467 0.74 ALDH1A1 (0.32)
SCHEMBL15202801 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1391439-A Synergistic herbicidal active substance combinations BAYER AG (DE) 2003-01-15 CN claimed
CN-1378424-A Selective herbicides on basis of n-aryl-trizoline (thio) ones BAYER AG (DE) 2002-11-06 CN claimed
US-5410095-A Reacting at least one perfluoromethoxyacetic acid derivatives with at least one hydroxylic compound selected from water, mono-alcohols, alkanediols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-04-25 US claimed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
EP-4743078-A2 APOL1 INHIBITORS AND METHODS OF USE Maze Therapeutics, Inc. (US) 2026-05-20 EP disclosed
US-20260083708-A1 IL-17 MODULATORS AND USES THEREOF NNOCARE PHARMA INC (US) 2026-03-26 US disclosed
CN-121586705-A Small molecule prostaglandin F receptor antagonists 辉凌公司 2026-02-27 CN disclosed
US-20250388595-A1 MODULATORS OF EUKARYOTIC INITIATION FACTOR 2B, COMPOSITIONS AND METHODS DENALI THERAPEUTICS INC (US) 2025-12-25 US disclosed
US-20250276924-A1 CHEMICAL AND BIOLOGICAL DEGRADATION OF ETHER PER- AND POLYFLUOROALKYL SUBSTANCES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-09-04 US disclosed
US-12391687-B2 Five-and-six-membered heterocyclic compound and use thereof as protein receptor kinase inhibitor SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD. (CN) 2025-08-19 US disclosed
US-20250206722-A1 SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS THE SCRIPPS RESEARCH INSTITUTE 2025-06-26 US disclosed
CN-102036943-A Preparation of a catalyst containing CF3Method for preparing compounds of O group MERCK PATENT GMBH 2011-04-27 CN disclosed
US-20110082312-A1 PRODUCTION OF COMPOUNDS COMPRISING CF30 GROUPS MERCK PATENT GESELLSCHAFT MIT DESCHRANKTER HAFTUNG (DE) 2011-04-07 US disclosed
US-20110082312-A1 PRODUCTION OF COMPOUNDS COMPRISING CF30 GROUPS MERCK PATENT GESELLSCHAFT MIT DESCHRANKTER HAFTUNG (DE) 2011-04-07 US disclosed
EP-2280918-A1 PRODUCTION OF COMPOUNDS COMPRISING CF3O GROUPS Merck Patent GmbH (DE) 2011-02-09 EP disclosed
WO-2009141053-A1 PRODUCTION OF COMPOUNDS COMPRISING CF3O GROUPS MERCK PATENT GMBH, (DE) 2009-11-26 WO disclosed
CN-1396953-A P450 monooxygenases of CYP79 family SYNGENTA PARTICIPATIONS AG (CH) 2003-02-12 CN disclosed
CN-1391439-A Synergistic herbicidal active substance combinations BAYER AG (DE) 2003-01-15 CN disclosed
CN-1378424-A Selective herbicides on basis of n-aryl-trizoline (thio) ones BAYER AG (DE) 2002-11-06 CN disclosed
US-5410095-A Reacting at least one perfluoromethoxyacetic acid derivatives with at least one hydroxylic compound selected from water, mono-alcohols, alkanediols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-04-25 US disclosed