SCHEMBL6935927

SCHEMBL6935927

COC(=O)C(=O)c1ccccc1Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.59
RAB9A P51151 1/20 0.57
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ALDH1A1 P00352 5/20 0.50
TSHR P16473 3/20 0.50
GAA P10253 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
HTT P42858 2/20 0.49
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
KDM4E B2RXH2 1/20 0.47
MAPK1 P28482 2/20 0.47
MAPK8 P45983 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HSD17B10 Q99714 1/20 0.47
HPGD P15428 1/20 0.47
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954675 0.90 KMT2A (0.61) CTNNB1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL9349914 0.89 HTT (0.55) CTNNB1RAB9AMEN1KMT2ATSHR
SCHEMBL22406943 0.87 MAPT (0.55) CTNNB1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL8954770 0.85 GAA (0.51) CTNNB1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL28218939 0.83 CTNNB1 (0.56) CTNNB1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL11589739 0.82 CTNNB1 (0.62) CTNNB1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL2540179 0.82 CTNNB1 (0.62) CTNNB1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL6932848 0.82 CTNNB1 (0.54) CTNNB1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL4782537 0.82 CTNNB1 (0.67) CTNNB1RAB9AMEN1KMT2AL3MBTL1
SCHEMBL6635028 0.82 CTSD (0.59) RAB9ATSHRGAASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6469195-B1 SUITABLE FOR USE AS CROP PROTECTION AGENTS AGAINST HARMFUL FUNGI BASF AKTIENGESELLSCHAFT (DE) 2002-10-22 US claimed
US-6566547-B1 3-alkoxy-2-phenylacrylic acid derivatives ZENECA LIMITED (GB) 2003-05-20 US disclosed
EP-0178826-B2 Fungicides SYNGENTA LTD (GB) 2003-04-09 EP disclosed
EP-0736001-B1 ARYL ACETIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1999-06-09 EP disclosed
EP-0736001-A1 ARYL ACETIC ACID DERIVATIVES BAYER AG (DE) 1996-10-09 EP disclosed
EP-0398692-B1 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI & CO (JP) 1996-08-21 EP disclosed
US-5548078-A FOR AGRICULTURE SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-08-20 US disclosed
WO-1995017376-A1 ARYL ACETIC ACID DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1995-06-29 WO disclosed
US-5401877-A Agricultural fungicide SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1995-03-28 US disclosed
EP-0629609-A1 Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-12-21 EP disclosed
US-5286894-A Phenyl acrylic acid derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-02-15 US disclosed
US-5185342-A ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-02-09 US disclosed
US-5157144-A Fungicides and plant growth regulators IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-10-20 US disclosed
US-5145954-A Fungicides, insecticides, plant growth regualtors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-09-08 US disclosed
EP-0178826-B1 FUNGICIDES ZENECA LIMITED (GB) 1991-12-18 EP disclosed
EP-0431328-A2 Fungicides ZENECA LIMITED (GB) 1991-06-12 EP disclosed
US-4999042-A Fungicides, plant growth regulators IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-03-12 US disclosed
EP-0398692-A2 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-11-22 EP disclosed
EP-0244077-A1 Sulphides derived from substituted phenyl-2-acrylic acid IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-11-04 EP disclosed
EP-0178826-A2 Fungicides ZENECA LIMITED (GB) 1986-04-23 EP disclosed