⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059095 | 1.00 | — | — | |
| SCHEMBL7227369 | 0.83 | — | — | |
| SCHEMBL28397952 | 0.81 | GSK3A (0.34) | — | |
| SCHEMBL11485098 | 0.79 | — | — | |
| SCHEMBL11573575 | 0.77 | — | — | |
| SCHEMBL4138702 | 0.71 | — | — | |
| SCHEMBL5766279 | 0.71 | ITGB3 (0.32) | — | |
| SCHEMBL11786304 | 0.71 | — | — | |
| SCHEMBL8980051 | 0.69 | — | — | |
| SCHEMBL8892558 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217828-B | Preparation method of lepistamycin and intermediate thereof | 浙江海正药业股份有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-111217828-A | Preparation method of lepithromycin and intermediate thereof | 浙江海正药业股份有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-1046275-C | 2-methoxyiminophenyl-N-methylacetamide derivatives, process for their preparation, their use and compositions containing them | BASF AG (DE) | 1999-11-10 | — | — | CN | claimed |
| EP-0686152-B1 | ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES | BASF AG (DE) | 1997-05-02 | — | — | EP | claimed |
| CN-1118165-A | Ortho-substituted 2-methoxyiminophenylacetic acid methylamides | BASF AG (DE) | 1996-03-06 | — | — | CN | claimed |
| CN-111217828-B | Preparation method of lepistamycin and intermediate thereof | 浙江海正药业股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-111217828-B | Preparation method of lepistamycin and intermediate thereof | 浙江海正药业股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-111217828-A | Preparation method of lepithromycin and intermediate thereof | 浙江海正药业股份有限公司 | 2020-06-02 | — | — | CN | disclosed |
| EP-0757042-B1 | Ortho-substituted 2-methoxyiminophenylaceticacid methylester | BASF AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| EP-0757042-A1 | Ortho-substituted 2-methoxyiminophenylaceticacid methylester | BASF Aktiengesellschaft (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-4463172-A | Process for producing 2-methyl cephem-2-em and 2-methylcephem-3-em derivitaves | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| EP-0035357-A1 | 2-Methylcephalosporins and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-09-09 | — | — | EP | disclosed |
| US-4182866-A | CEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-01-08 | — | — | US | disclosed |
| US-4178443-A | Derivatives of 7 [-substituted oxyimins acetamido] cephalosporins | HOFFMANN-LA ROCHE INC. (US) | 1979-12-11 | — | — | US | disclosed |