SCHEMBL6936104

SCHEMBL6936104

[SiH3]C1c2ccccc2-c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 3/20 0.46
HTR2A P28223 2/20 0.46
CYP19A1 P11511 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
POLB P06746 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
ACHE P22303 3/20 0.37
BCHE P06276 2/20 0.37
CHRM2 P08172 1/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
CHRM1 P11229 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7944465 0.97 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL2785223 0.94 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL28480527 0.84 MEN1 (0.52) CYP19A1NCOR2POLBCYP1A2BCHE
Hydrochloric Acid SCHEMBL3385863 0.75 GPR3 (0.46) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL27602853 0.75 GPR3 (0.37) GPR3HTR2APOLBACHECHRM2
SCHEMBL524603 0.73 GPR3 (0.50) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL29950614 0.73 GPR3 (0.50) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL27585043 0.73 GPR3 (0.35) GPR3HTR2ACYP19A1POLB
SCHEMBL6814556 0.73 HTR2A (0.50) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL1985361 0.73 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805423-A Synthesis method of 9, 9-difluoro-9-silafluorene 石家庄圣泰化工有限公司 2022-07-29 CN claimed
CN-110343127-A A kind of preparation method of 9- silicon fluorene derivative 中国科学院化学研究所 2019-10-18 CN claimed
EP-0900228-B1 A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES DOW CHEMICAL CO (US) 2002-06-12 EP claimed
EP-0900228-A1 A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1999-03-10 EP claimed
WO-1997041134-A1 A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-11-06 WO claimed
US-5670680-A Method for producing octahydrofluorenyl metal complexes THE DOW CHEMICAL COMPANY (US) 1997-09-23 US claimed
CN-1127759-A Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM CO (US) 1996-07-31 CN claimed
EP-4714962-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2026-03-25 EP disclosed
US-11795388-B2 High luminescence plastic scintillators NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2023-10-24 US disclosed
US-20230051031-A1 MULTI-FUNCTIONAL HYBRID MATERIAL BASED ON SEPIOLITE FOR ENVIRONMENTAL RECOVERY AND BIO-REMEDIATION CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2023-02-16 US disclosed
US-20220403235-A1 High Luminescence Plastic Scintillators NAT TECH & ENG SOLUTIONS SANDIA LLC (US) 2022-12-22 US disclosed
US-11479717-B1 High luminescence plastic scintillators NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2022-10-25 US disclosed
CN-114805423-A Synthesis method of 9, 9-difluoro-9-silafluorene 石家庄圣泰化工有限公司 2022-07-29 CN disclosed
US-5591879-A INTERMEDIATES FOR METALLOCENE POLYMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1997-01-07 US disclosed
US-5578741-A OLEFIN POLYMERIZATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1996-11-26 US disclosed
US-5565396-A METALLOCENE AND AN ORGANOALUMINOXANE COCATALYST FOR HOMO OR COPOLYMERIZING OLEFINS PHILLIPS PETROLEUM COMPANY (US) 1996-10-15 US disclosed
US-5563284-A COORDINATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1996-10-08 US disclosed
CN-1131670-A Organoaluminoxy product, catalyst systems, preparation, and use PHILLIPS PETROLEUM CO (US) 1996-09-25 CN disclosed
US-5554795-A Process for preparing cyclopentadienyl-type ligands PHILLIPS PETROLEUM COMPANY (US) 1996-09-10 US disclosed
CN-1127759-A Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM CO (US) 1996-07-31 CN disclosed