Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.56 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936135 | 1.00 | MAPT (0.62) | MAPTALDH1A1GAAGSTP1GSTM2 | |
| SCHEMBL10650251 | 0.88 | MAPT (0.79) | MAPTALDH1A1GAAGSTP1GSTM2 | |
| SCHEMBL6936618 | 0.85 | MAPT (0.57) | MAPTALDH1A1GAAHTTMEN1 | |
| SCHEMBL18779462 | 0.85 | MAPT (0.63) | MAPTALDH1A1GAAGSTP1GSTM2 | |
| SCHEMBL7989054 | 0.83 | MAPT (0.60) | MAPTALDH1A1GAAGSTP1GSTM2 | |
| SCHEMBL810413 | 0.81 | MAPT (0.53) | MAPTALDH1A1GAAHTTMEN1 | |
| SCHEMBL2962044 | 0.81 | GSTP1 (0.61) | MAPTALDH1A1GAAGSTP1GSTM2 | |
| SCHEMBL19048781 | 0.79 | MAPT (0.62) | MAPTALDH1A1GAAGSTP1GSTM2 | |
| SCHEMBL1455551 | 0.79 | MAPT (0.51) | MAPTALDH1A1GAAHTTMEN1 | |
| SCHEMBL1923978 | 0.78 | BCL2L1 (0.74) | MAPTALDH1A1GAAGSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086079-B1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA A S (CZ) | 2003-05-07 | — | — | EP | disclosed |